Plasma rich platelet injection, commonly known as P shot, is a blood component believed to aid in healing and tissue regeneration. P-shot therapy is often utilized for healing muscle or tendon injuries, enhancing hair growth, and accelerating post-surgery recovery.

Plasma rich platelet injection is also explored as a treatment or an alternative approach for various conditions, including:

  • Erectile dysfunction (ED)
  • Peyronie’s disease
  • Penis enlargement
  • Improving sexual performance

The effectiveness of Plasma rich platelet injection in treating ED has limited research backing it up. In this article, we will delve into what scientific studies have revealed so far about Plasma rich platelet injection.

Additionally, we’ll examine other treatment alternatives and the potential side effects associated with Plasma rich platelet injection

Plasma rich platelet injection How does it work?

Plasma Rich Platelet Injection in ED Treatment

Your blood consists of four primary elements: red cells, white cells, plasma, and platelets.

Plasma, the liquid component of blood, comprises about half of its total volume. Platelets play a crucial role in blood clotting following an injury and contain growth factors, which are proteins that accelerate healing.

The proposed advantage of P shot for ED is its potential to improve the health of penile tissues and blood vessels.

The process of creating plasma rich platelets begins with a healthcare professional drawing a small amount of your blood. This blood is then placed in a device known as a centrifuge, which spins rapidly to separate the plasma and platelets from the other blood components.

This separation results in a plasma rich platelets mixture that has a significantly higher concentration of platelets than normal blood. Once prepared, the P shot is injected into the penis, a procedure commonly referred to as the Priapus Shot or P Shot.

The P Shot is typically a swift process, usually allowing patients to leave the clinic within an hour. There’s no special preparation required before undergoing this procedure.

Plasma Rich Platelet Injection vs. Other ED Treatments

p shot treatment in Turkey Erectile dysfunction treatment in Turkey

Plasma rich platelet injection therapy is a relatively newer approach in the field of erectile dysfunction treatment and is still under research for its efficacy and safety. Here’s how it compares to traditional erectile dysfunction treatment:

Plasma rich platelet injection Therapy:

    • plasma rich platelets therapy involves injecting platelet-rich plasma derived from the patient’s own blood into the penis, with the aim of stimulating tissue regeneration and improving blood flow.
    • The effectiveness of P shot therapy for ED is still under investigation, and there’s limited scientific evidence to support its use as a reliable treatment option at this point.
    • It’s considered experimental, and more research is needed to establish its safety, efficacy, and long-term outcomes.

Traditional ED Treatments:

    • Medications: These are often the first line of treatment for ED. Medications like sildenafil (Viagra), tadalafil (Cialis), and others work by relaxing the blood vessels in the penis, increasing blood flow, and facilitating an erection in response to sexual stimulation.
    • Lifestyle Changes: Improving physical activity, adopting a healthier diet, and quitting smoking can significantly improve ED. These changes address the root causes of ED, particularly those related to cardiovascular health.
    • Talk Therapy: Psychological factors like stress, anxiety, and relationship issues can contribute to ED. Talk therapy can be effective in these cases, helping address the psychological barriers to sexual function.
    • Targeting Underlying Conditions: Often, ED is a symptom of an underlying health condition such as high blood pressure, obesity, or heart disease. Managing these conditions can improve or even resolve ED.

Given the current state of research, traditional treatment options are generally recommended over P shot therapy, unless part of a clinical trial. 

It’s essential for patients to discuss the best treatment plan with their healthcare provider, taking into consideration the underlying causes of their ED, their overall health, and the safety and efficacy of the treatment options available.

Combining Plasma Rich Platelet Injection and ESWT Treatments

Eswt and p shot

Yes, plasma rich platelets injection treatment can be applied simultaneously with ESWT (Extracorporeal Shock Wave Therapy) for the treatment of erectile dysfunction. 

This combination is a topic of interest in the medical community, and there is literature suggesting that these two treatments can be administered together.

In clinical practice, some healthcare providers recommend this combined approach to suitable patients. Administering plasma rich platelets injection and ESWT treatments concurrently does not typically result in negative effects. 

Since both treatments work through similar mechanisms – enhancing tissue regeneration and blood flow – they may potentially amplify each other’s effectiveness.

However, it’s crucial for patients to consult with their healthcare provider to determine if this combined treatment approach is appropriate for their individual health condition and treatment goals.

Start of Plasma Rich Platelet Injection Effects

Plasma Rich Platelet Injection for ed treatment in Turkey

The effects of Penile P shot (Platelet-Rich Plasma) treatment typically reach their peak around three months after the procedure. 

It is suggested that the benefits of this treatment can be long-lasting, and in some cases, possibly permanent. However, it’s important to note that the efficacy of P shot treatment varies from one individual to another.

Several factors can influence the effectiveness of plasma rich platelets injection treatment, including:

  • The patient’s age: As age increases, the regenerative capabilities of the body may decrease, potentially affecting the treatment’s effectiveness.
  • Lifestyle habits: Smoking and alcohol consumption can negatively impact the body’s healing and regenerative processes.
  • Obesity: Excess weight can lead to various health issues that might interfere with the treatment’s efficacy.
  • Diabetes: This condition can affect blood flow and tissue healing, thereby influencing the response to P shot treatment.
  • High blood pressure: Hypertension can impact vascular health, which is crucial for the effectiveness of treatments like P shot for erectile dysfunction.

Therefore, the overall health and lifestyle of the patient play a significant role in determining the response to Plasma rich platelet injection treatment. It’s always recommended to discuss with a healthcare provider to understand how these factors might affect individual treatment outcomes.

Can i Repeating P Shot Treatments?

p shot for ed treatment

Yes, plasma rich platelets injection  treatment can be administered multiple times. Because plasma rich injection is derived from the patient’s own blood, it typically has a low risk of serious side effects, making it suitable for repeated applications. The procedure’s safety profile allows for its use at various intervals as needed.

The recommended frequency for repeating plasma rich injection treatment can vary, but a common protocol suggests administering a single dose at intervals of 3, 6, and 12 months. This schedule is designed to optimize the treatment’s effectiveness while allowing the body sufficient time to respond to each treatment session.

However, the specific frequency and number of treatments may be adjusted based on individual patient needs, the condition being treated, and the patient’s response to initial treatments.

It’s important for patients to have a detailed discussion with their healthcare provider to determine the most appropriate treatment schedule tailored to their unique circumstances.

Timeline for Sex After P Shot Injection

After receiving a plasma rich platelets injection (Priapus Shot), which involves the application of P-shot (Platelet-Rich Plasma) to the penis, patients generally do not need to abstain from sexual activity for an extended period. 

This is because the plasma rich injection is a non-invasive procedure and typically does not cause severe pain, significant swelling (edema), or hematoma in the penis.

How much does a plasma rich injection cost?

Opting for plasma rich injection treatment in Istanbul offers a notable financial advantage compared to most countries in the world such as the United States, Canada, Europe, and Australia. The cost of P shot therapy in Istanbul is generally lower, influenced by factors such as the local economic conditions, competition among healthcare providers, and the overall cost of living in the region. 

As a hub for medical tourism, Istanbul provides an opportunity for individuals seeking more affordable options for P-shot treatment while ensuring access to professional healthcare services. 

To obtain accurate and up-to-date information on the cost, prospective patients are encouraged to directly inquire with reputable healthcare providers or clinics in Istanbul, such as the Istanbul Urology Clinic, where experienced professionals can offer insights into the procedure, associated costs, and ensure adherence to high standards of safety and professionalism.

Finding a doctor

erectile dysfunction treatment

If you’re considering plasma rich injection for Erectile dysfunction treatment, it’s advisable to consult with the Istanbul Urology Clinic. They can provide detailed information about P-shot and refer you to a qualified doctor within their team who specializes in administering this treatment.

At the Istanbul Urology Clinic, the plasma rich injection procedure for erectile dysfunction is typically carried out by a medically trained professional, such as a doctor or surgeon. They have the expertise and experience to perform this specialized treatment effectively.

Risks and side effects of P shot Therapy

Plasma Rich Platelet Injection

The application of plasma rich injection (Platelet-Rich Plasma) therapy is generally considered safe due to its autologous nature, meaning it’s derived from the patient’s own blood. This significantly reduces the risk of certain complications typically associated with other treatments. Key points regarding the side effects of P-shot include:

  1. Minimal Negative Side Effects: Since plasma rich injection is created from a patient’s own blood, it inherently carries fewer risks of adverse effects compared to treatments that introduce foreign substances into the body.
  2. Low Risk of Infection: When plasma rich injection is administered under sterile conditions, the risk of infection is considerably low. Sterility during the preparation and application process is crucial to prevent any potential contamination.
  3. No Allergic Reactions: The likelihood of an allergic reaction is minimal with plasma rich injection therapy because the plasma used is sourced from the patient’s body, eliminating the risk of immune system reactions to foreign substances.

However, it’s important to remember that while P-shot is largely safe, the process of obtaining blood and the injection itself may carry some general risks, as with any medical procedure involving needles. 

These risks, albeit minor, can include pain at the injection site, bruising, or bleeding.

Patients considering P-shot therapy should discuss these aspects with their healthcare provider to fully understand the procedure and any potential risks based on their individual health condition.

FAQs About Plasma Rich Platelet 

The procedure may cause some discomfort, but it’s generally well-tolerated. Anesthetic cream can be applied to minimize pain.


The procedure typically takes about 30 minutes to an hour.


This can vary. Some patients may see improvement after a single treatment, while others might need multiple sessions.


Some patients may experience temporary swelling or bruising. Improvement in erectile function may take a few weeks to become noticeable.


The long-term efficacy of PRP injections for ED is not well-established. Some patients may need periodic treatments to maintain results.

Typically, there is minimal to no downtime. Patients can usually return to their normal activities shortly after the procedure.


PRP is a regenerative therapy, potentially offering longer-term benefits by promoting tissue healing, unlike PDE5 inhibitors which are taken before sexual activity. Its effectiveness compared to other treatments can vary by individual.


PRP may aid in tissue repair and improve blood flow, but it’s not known to reverse the underlying causes of ED, especially if they are related to chronic conditions like diabetes or heart disease.


There are no specific age restrictions, but the treatment’s effectiveness and appropriateness might vary depending on the individual’s age and overall health.


PRP may aid in the recovery of nerve and tissue damage, but its effectiveness in post-prostate surgery ED cases is not conclusively established and should be evaluated by a healthcare provider.


Generally, no special preparation is needed. However, it’s important to disclose all medications and supplements to the treating physician, as some might need to be paused.


Adopting healthier lifestyle choices, like regular exercise, a balanced diet, and quitting smoking, can potentially enhance the effectiveness of PRP treatment.


The duration of PRP’s effects varies. Some patients report lasting improvements for several months, while others may require repeat treatments..


plasma rich injection therapy remains in the experimental stages for treating erectile dysfunction (ED). Currently, there is no definitive evidence to confirm its effectiveness in treating ED. Additionally, this procedure is relatively costly and is not typically covered by most insurance plans.

While initial research findings are encouraging, conclusive evidence from larger-scale studies and controlled trials is still awaited. In light of this, it might be advisable to adhere to more traditional ED treatments that have established efficacy and safety profiles.

If you are experiencing difficulties in achieving an erection, consulting with a healthcare professional is important. A doctor can conduct necessary tests to identify any underlying medical conditions that might be contributing to ED and can recommend suitable treatment options based on your specific health needs.

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